Publications MPI-CBG TDS

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Publications in 2014

  Title
Sundaramurthy-2014 Deducing the mechanism of action of compounds identified in phenotypic screens by integrating their multiparametric profiles with a reference genetic screen
Anitei-2014 A high-throughput siRNA screen identifies genes that regulate mannose 6-phosphate receptor trafficking.
Borg-2014 Mesenchymal stromal cells improve transplanted islet survival and islet function in a syngeneic mouse model.

Publications in 2013

  Title
Zanin-2013 A conserved RhoGAP limits M phase contractility and coordinates with microtubule asters to confine RhoA during cytokinesis
Dibenedetto-2013 Calcineurin A versus NS5A-TP2/HD domain containing 2: a case study of site-directed low-frequency random mutagenesis for dissecting target specificity of peptide aptamers
Stöter-2013 Cell Profiler and KNIME: Open Source Tools for High Content Screening
Gilleron-2013 Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape
Sundaramurthy-2013 Integration of Chemical and RNAi Multiparametric Profiles Identifies Triggers of Intracellular Mycobacterial Killing
Eugster-2013 Measuring T cell receptor and T cell gene expression diversity in antigen-responsive human CD4+ T cells
Ivanova-2013 Age-dependent labeling and imaging of insulin secretory granules

Publications in 2012

  Title
Bickle-2012 Systems drug discovery: a quantitative, objective approach for safer drug development
Winter-2012 Caenorhabditis elegans screen reveals role of PAR-5 in RAB-11-recycling endosome positioning and apicobasal cell polarity
Foret-2012 A General Theoretical Framework to Infer Endosomal Network Dynamics from Quantitative Image Analysis

Publications in 2011

  Title
Ettinger-2011 Proliferating versus differentiating stem and cancer cells exhibit distinct midbody-release behaviour

Publications in 2010

  Title
Collinet-2010 Systems survey of endocytosis by multiparametric image analysis
Slabicki-2010 A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia
Bickle-2010 The beautiful cell: high-content screening in drug discovery
Farhan-2010 MAPK signaling to the early secretory pathway revealed by kinase/phosphatase functional screening

Publications in 2009

  Title
Niederlein-2009 Image Analysis in High-Content Screening
Bramsen-2009 A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity

Publications in 2008

  Title
Krausz-2008 High-content siRNA screening for target identification and validation
Bickle-2008 High-content screening: a new primary screening tool?
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