Biopolis Dresden Imaging Platform

HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity.

Lawo S, Bashkurov M, Mullin M, Ferreria MG, Kittler R, Habermann B, Tagliaferro A, Poser I, Hutchins JR, Hegemann B, Pinchev D, Buchholz F, Peters JM, Hyman AA, Gingras AC, Pelletier L

The assembly of a robust microtubule-based mitotic spindle is a prerequisite for the accurate segregation of chromosomes to progeny. Spindle assembly relies on the concerted action of centrosomes, spindle microtubules, molecular motors, and nonmotor spindle proteins.

Fig.1 taken from Lawo et al, 2009.
  • Curr. Biol. 2009 May 26;19(10):816-26
  • 2009
  • Cell Biology
  • 19427217
  • PubMed

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