Biopolis Dresden Imaging Platform

Spatial discontinuity of optomotor-blind expression in the Drosophila wing imaginal disc disrupts epithelial architecture and promotes cell sorting.

Shen J, Dahmann C, Pflugfelder GO

Decapentaplegic (Dpp) is one of the best characterized morphogens, required for dorso-ventral patterning of the Drosophila embryo and for anterior-posterior (A/P) patterning of the wing imaginal disc. In the larval wing pouch, the Dpp target gene optomotor-blind (omb) is generally assumed to be expressed in a step function above a certain threshold of Dpp signaling activity.

Fig.4 taken from Shen et al, 2010.
  • BMC Dev. Biol. 2010 Feb 23;10:23
  • 2010
  • Developmental Biology
  • 20178599
  • PubMed

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