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The chemokine receptor cxcr5 regulates the regenerative neurogenesis response in the adult zebrafish brain.

Kizil C, Dudczig S, Kyritsis N, Machate A, Blaesche J, Kroehne V, Brand M

Unlike mammals, zebrafish exhibits extensive neural regeneration after injury in adult stages of its lifetime due to the neurogenic activity of the radial glial cells. However, the genes involved in the regenerative neurogenesis response of the zebrafish brain are largely unknown. Thus, understanding the underlying principles of this regeneration capacity of the zebrafish brain is an interesting research realm that may offer vast clinical ramifications.

Fig.6 taken from Kizil et al, 2012.
  • Neural Dev 2012 Jul 23;7:27
  • 2012
  • Neurobiology
  • 22824261
  • PubMed

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