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Electron Microscopy Facility (EMF)

Max Planck Institute of Molecular Cell Biology and Genetics

We offer the technology, expertise and resources to study biological samples in the range of individual molecules to organoids and tissues. Our routine techniques include negative staining and resin embedding for investigations conducted at room temperature. Additionally, we are equipped to analyze vitrified samples at the near-native state using both fluorescence light and electron microscopy. While our facility specializes in transmission electron microscopy (TEM), we are currently expanding our capabilities to include large-volume acquisitions through scanning electron microscopy (SEM). Furthermore, we are actively developing workflows for correlative light and electron microscopy (CLEM) at both 2D and 3D scales. We are happy to discuss your project and collaborate to find the best possible solution for your research needs.

Techniques

  • negative staining of small samples and biomolecules
  • Immobilization of cells and tissues through aldehyde crosslinking
  • cryo-immobilization of cells and tissues via plunge or high-pressure freezing
  • Immunolabelling (pre- and post-embedding) of endogenous proteins on resin- or cryosections

Specialities

  • TEM in 2D and 3D (tomography
  • SEM in 2D and 3D (FIB-SEM and SBF-SEM
  • (cryo) Fluorescence light microscopy on bright field and confocal laser scanning microscopes
  • (cryo) CLEM in 2D and 3D
  • In Addition, we help users with data curation, analysis and visualization.

Team

Photo of Felix Lange © MPI-CBG

Felix Lange

 

Facility Leader

Placeholder for Tobias Fürstenhaupt © BioDIP

Tobias Fürstenhaupt

EM Specialist

Placeholder for the portrait image of a man © BioDIP

Matthias Pöge
 

EM Specialist

Photo of Jana Meissner © MPI-CBG

Jana Meissner
 

Technical Assistant

Michaela Yuan © MPI-CBG

Michaela Yuan
 

Technical Assistant

Photo of Weihua Leng © MPI-CBG

Weihua Leng
 

Technical Assistant

Visitor's Address

Max Planck Institute of Molecular Cell Biology and Genetics
Electron Microscopy Facility
Pfotenhauerstrasse 108 
01307 Dresden
Germany

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