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Biophysics Core Facility (BCF)

Max Planck Institute of Molecular Cell Biology and Genetics

The Biophysics Core Facility (BCF) provides researchers with the technologies and expertise to study biophysical mechanisms of living systems at scales bridging from single molecules to tissues and organs. In addition, the facility also brings novel light microscopy methods to the institute at an early prototype stage by collaborating with developer labs and companies.

As a user facility, the BCF provides training and support to enable researchers to work independently. The focus of the facility is to enable new experimental designs by developing workflows together with users. To foster access to biophysics and to ensure a high standard of experiments, the BCF maintains and refines pipelines to measure, automate, and analyze physical variables and properties including forces, flows, and elasticity. The facility also supports advanced imaging techniques such as ultrafast volumetric imaging, fluorescence lifetime imaging microscopy, fluorescence correlation spectroscopy, and single-molecule localization microscopy (SMLM) both within the BCF and in collaboration with the LMF. 

Techniques

  • Optical Tweezers
  • Nanoindentation
  • Micropatterning
  • Single-Objective Light Sheet Microscopy

Specialities

  • Workflows for biophysical experiments
  • Custom-building of light microscopy systems
  • Ultra-fast volumetric imaging
  • Fluorescence Lifetime Imaging Microscopy (FLIM)
  • DNA points accumulation for imaging nanoscale topography (DNA-PAINT)

Team

Sebastian Bundschuh © MPI-CBG

Sebastian Bundschuh

Facility Leader

Nazar Oleksiievets © MPI-CBG

Nazar Oleksiievets

Optical Engineer

Michael Bugiel © MPI-CBG

Michael Bugiel

Biophysicist

Visitor's Address

Max Planck Institute of Molecular Cell Biology and Genetics
Biophysics Core Facility (BCF)
Pfotenhauerstr. 108
01307 Dresden
Germany

Postal Address

Max Planck Institute of Molecular Cell Biology and Genetics
Biophysics Core Facility (BCF)
Pfotenhauerstr. 108
01307 Dresden
Germany

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